Nippon Rinsho. 2003 Aug;61(8):1355-60
Department of Neurology, Jikei University School of Medicine.
In spite of the proven efficacy of the newer immunomodulative pharmacologic treatments for multiple sclerosis, such as steroid pulse therapy for exacerbation and beta-interferon subcutaneous injections for prevention, those treatments have not yet satisfied the criteria for direct management of the disease.
Thus, even now, patients with multiple sclerosis still need symptomatic therapy to improve their quality of life and ameliorate the impairments in their activities of daily living due to their various neurologic deficits.
This article reviews the management of a wide range of neurologic symptoms of multiple sclerosis, including spasticity, bladder dysfunction, paroxysmal symptoms, and chronic pain.