Zh Nevrol Psikhiatr Im S S Korsakova. 2003;Spec No 2:83-90
The review addresses an analysis of the causes of neurodegenerative process development in multiple sclerosis (MS) as well as the modern approaches to the treatment of the disease.
The best-studied mechanisms of degenerative alterations and clinical and experimental evidence supported the protective influence of beta-interferons treatment in MS are discussed.
Neuroprotection is highlighted among the future directions.
The main features of the various groups of neurotrophic factors and the possible ways of their therapy-targeted transport into brain tissues are analyzed.