All About Multiple Sclerosis

More MS news articles for September 2003

Use of botulinum toxin type B for the treatment of detrusor hyperreflexia in a patient with multiple sclerosis: a case report

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=13680581&dopt=Abstract

Arch Phys Med Rehabil. 2003 Sep;84(9):1399-400
Dykstra DD, Pryor J, Goldish G.
Department of Physical Medicine and Rehabilitation, Univeristy of Minnesota, MN 55455, USA.

We describe a patient with multiple sclerosis (MS) who had detrusor hyperreflexia that was not responsive to oral medications or clean intermittent catheterization.

This patient was successfully treated with 2 separate injections of botulinum toxin type B into the bladder.

The results of the treatment lasted 4 months and there were no side effects.

A cystometrogram (CMG) done before the botulinum toxin type B injections showed significant detrusor instability.

A repeat CMG months later showed no detrusor instability.

To our knowledge, this is the first reported successful use of botulinum toxin type B in a patient with detrusor hyperreflexia from MS.