More MS news articles for September 2002

Proposed diagnostic criteria and nosology of acute transverse myelitis

Neurology 2002 Aug 27;59(4):499-505
Transverse Myelitis Consortium Working Group.

Acute transverse myelitis (ATM) is a focal inflammatory disorder of the spinal cord, resulting in motor, sensory, and autonomic dysfunction.

A set of uniform diagnostic criteria and nosology for ATM is proposed to avoid the confusion that inevitably results when investigators use differing criteria.

This will ensure a common language of classification, reduce diagnostic confusion, and lay the groundwork necessary for multicenter clinical trials.

In addition, a framework is suggested for evaluation of individuals presenting with signs and symptoms of ATM.

Best treatment often depends on a timely and accurate diagnosis.

Because acute transverse myelopathies are relatively rare, delayed and incomplete work-ups often occur.

Rapid and precise diagnosis will ensure not only that compressive lesions are detected and treated but also that idiopathic ATM is distinguished from ATM secondary to a known underlying disease.

Identification of etiologies may suggest medical treatment, whereas no clearly established medical treatment currently exists for idiopathic ATM.

Establishment of a diagnostic algorithm will likely lead to improved care, although it is recognized that the entire evaluation may not be performed for each patient.