http://www.neurology.org/cgi/content/abstract/57/5/889

P. O’Connor, MD, FRCPC;, L. Lee, MD, FRCPC;, P. Tin Ng, PhD;, P. Narayana, PhD, DABR; and J. S. Wolinsky, MD
From St. Michael’s Hospital (Dr. O’Connor), Sunnybrook and Women’s College Health Sciences Centre (Dr. Lee), and Atkinson Faculty of Liberal and Professional Studies, York University (Dr. Ng), Toronto, Ontario, Canada; and University of Texas–Houston Medical School (Dr. Narayana) and Houston Health Science Centre, University of Texas (Dr. Wolinsky).

Address correspondence and reprint requests to Dr. P. O’Connor, St. Michael’s Hospital, 30 Bond St., Rm. 3007, Shuter Wing, Toronto, Ontario, Canada M5B 1W8.

Twenty-nine patients with secondary progressive MS underwent monthly assessment with Expanded Disability Status Scale (EDSS), MS Functional Composite (MSFC), MS Quality of Life-54, and cranial MRI over 6 months.

Overall quality of life (OQOL) correlated highly with emotional well-being, the mental health composite, health distress, and the physical health composite.

In contrast, there was no statistical evidence of consistent correlation between OQOL and EDSS, MSFC, or MR outcome measures.