All About Multiple Sclerosis

More MS news articles for October 2002

Analysis of -631 and -475 interleukin-2 promoter single nucleotide polymorphisms in multiple sclerosis

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12358847&dopt=Abstract

Eur J Immunogenet 2002 Oct;29(5):389-90
Fedetz M, Alcina A, Fernandez O, Guerrero M, Delgado C, Matesanz F.

We have analysed the interleukin-2 (IL-2) promoter single nucleotide polymorphisms -475 A/T and -631 G/A, relative to the initiation codon, in patients with multiple sclerosis (MS) and in healthy controls.

Both groups showed a very low frequency of T at -475 and A at -631.

Our results suggest that these polymorphisms do not contribute to MS susceptibility.