Eur J Immunogenet 2002 Oct;29(5):389-90
Fedetz M, Alcina A, Fernandez O, Guerrero M, Delgado C, Matesanz F.
We have analysed the interleukin-2 (IL-2) promoter single nucleotide polymorphisms -475 A/T and -631 G/A, relative to the initiation codon, in patients with multiple sclerosis (MS) and in healthy controls.
Both groups showed a very low frequency of T at -475 and A at -631.
Our results suggest that these polymorphisms do not contribute to MS susceptibility.