Pathol Biol (Paris) 2002 Aug;50(7):463-8
Chidiac C, Braun E.
Service des Maladies Infectieuses et Tropicales, CISIH de Lyon, Hopital de la Croix-Rousse, F69317 Lyon, France.
Herpesviridae are ubiquitous, and are commonly involved in well identified diseases as genital herpes, chickenpox and herpes zoster, infectious monucleosis, exanthem subitum...
They are responsible for latent and chronic infections after primo infestation. Atherosclerosis, multiple sclerosis, Alzheimer's disease are diseases which are very different, and for which pathogenesis remains unknown.
Several authors have hypothesized that Herpesviridae could play a role in such diseases.
The present paper reviews arguments not only in favour but also against such hypothesis. Any formal conclusion is impossible, and more extensive studies are warranted.