All About Multiple Sclerosis

More MS news articles for November 2003

Measuring personality and emotional functioning in multiple sclerosis: a cautionary note

Arch Clin Neuropsychol. 2003 May;18(4):419-29
Nelson LD, Elder JT, Tehrani P, Groot J.
Neurology Department, University of California, Irvine, Medical Center, 101 The City Drive, Route 81, Building 53, Room 225, Orange, CA 92868, USA.

Changes in personality and emotional status are common in individuals with multiple sclerosis (MS).

The purpose of this study was to examine results based on the MMPI-2 before and following application of a statistical correction procedure (Gass, 1992).

This was done to help determine changes in scale score elevations when items containing actual physical symptoms are identified and statistically removed.

Twenty-eight participants with MS were administered the MMPI-2, then retested 1 year later.

Stability of MMPI-2 scores over time was demonstrated.

Results showed that when the correction procedure was applied to the MMPI-2, eight standard clinical scale scores dropped an average of 6.66 T-score points.

Significant differences were obtained between standard MMPI-2 scored profiles and corrected profiles on Scales 1-3 and 8.

Cautious interpretation of MMPI-2 results for neurological samples was indicated.

This study extended prototypic research by using patients with MS, examining the stability of results over time (1 year), and introducing a more reliable method of deriving standard T-scores in the correction procedure.