Multiple Sclerosis, 1 December 2003, vol. 9, no. 6, pp. 630-632(3)
Jaffe S.L.; Glabus M.F.; Kelley R.E.; Minagar A.
 Department of Neurology, Louisiana State University School of Medicine - Shreveport, 1501 Kings Highway, Shreveport, LA 71130, USA  Department of Psychiatry, Louisiana State University School of Medicine - Shreveport, 1501 Kings Highway, Shreveport, LA 71130, USA
Cortical speech disorders rarely occur in multiple sclerosis (MS).
We report a patient with relapsing-remitting MS, who presented with acute verbal dyspraxia.
Magnetic resonance imaging (MRI) demonstrated an acute T2/Flair hyperintense, primarily white matter lesion underlying the middle third of the inferior frontal gyrus.
The verbal dyspraxia cleared beginning 48 hours after the initiation of iv dexamethasone.
Follow-up MRI demonstrated qualitative and quantitative diminution of the hyperintensity.
This is the first report of a clinically definite MS patient with acute verbal dyspraxia.
Moreover,there was a suggestive localization of verbal praxis to Brodmann areas 44/45.