All About Multiple Sclerosis

More MS news articles for November 2002

Organic solvents and the risk of multiple sclerosis

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12410015&dopt=Abstract

Epidemiology 2002 Nov;13(6):718-20
Riise T, Moen BE, Kyvik KR.

BACKGROUND

Epidemiologic studies suggest that environmental factors may be part of the yet unknown causation of multiple sclerosis (MS). Several case-control studies have shown a history of elevated exposure to organic solvents among cases.

METHODS

Three cohorts of 11,542 painters, 36,899 construction workers and 9,314 food-processing workers were identified by the 1970 census in Norway. The cohorts were followed until the end of 1986 for registration of disability pensions.

RESULTS

A total of nine painters, 12 construction workers and six food workers had received a disability pension because of MS. The relative risk for painters compared with workers not exposed to organic solvents was 2.0 (95% confidence inter-val = 0.9-4.5) for MS.

CONCLUSIONS

These results are compatible with the hypothesis of organic solvents being a possible risk factor for MS.