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Body composition in ambulatory women with multiple sclerosis

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12422325&dopt=Abstract

Arch Phys Med Rehabil 2002 Nov;83(11):1559-1561
Lambert CP, Lee Archer R, Evans WJ.
Nutrition, Metabolism, and Exercise Laboratory, Donald W. Reynolds Department of Geriatrics (Lambert, Evans) and Department of Neurology (Archer), University of Arkansas for Medical Sciences, Little Rock, AR; and Central Arkansas Veterans Healthcare System, Little Rock, AR (Lambert, Evans).

OBJECTIVE:

To compare whole-body fat mass and fat-free mass (FFM) in ambulatory patients with multiple sclerosis (MS) and control subjects without MS.

DESIGN:

Nonrandomized controlled trial or cross-sectional study.

SETTING:

An exercise physiology laboratory at a medical school.

PARTICIPANTS:

Seventeen ambulatory patients with MS and 12 control subjects (all subjects were women). The median Expanded Disability Status Scale (EDSS) score was 4.0 for the individuals with MS.

INTERVENTIONS:

Not applicable.

MAIN OUTCOME MEASURES:

Whole-body percentage of fat-free mass (%FFM), percentage of body fat (%BF), FFM, and fat mass.

RESULTS:

A significant difference in age was observed between the groups; thus, age was used as a covariate in the body composition analyses. No significant differences were observed between the groups in %BF: 32.5+/-13.9 and 27.8+/-5.6 (P=.54) for MS and controls, respectively, or %FFM, 67.1+/-14.9 and 71.3+/-12.4 (P=.42) for MS and controls, respectively. For individuals with MS, no significant relation was observed between EDSS score and %BF (P=.24) or between EDSS score and %FFM (P=.24).

CONCLUSION:

No significant differences were observed in body composition between ambulatory MS patients and controls. Furthermore, the EDSS score was not a significant predictor of %BF or %FFM for people with MS.

© Copyright 2002 by the American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation