November 19, 2001
 

Grant title	Principal grantholder	Principal location
Characterisation of adult oligodendrocyte progenitors in the adult CNS with new cell-type specific markers	Professor PJ Brophy	Edinburgh University
The Multiple Sclerosis Society UK Tissue Bank	Professor R Reynolds	Imperial College, London
Site directed lesions of demyelination in viral models of MS	Dr JK Fazakerley	Edinburgh University
Molecules that mediate oligodendrocyte-axon interaction	Professor PJ Brophy	Edinburgh University
Investigation of brain endothelial cell mechanisms controlling migration into the CNS: Identification of potential therapeutic targets.	Greenwood, Professor J	Institute of Ophthalmology, London
491/I193398 A magnetic resonance study of the pathogenesis and prognosis of multiple sclerosis	Professor DH Miller	Institute of Neurology, London
Psychosocial aspects of caring: the role of social support and social networks for carers of people with multiple sclerosis	Mrs RA Chesson	Robert Gordon University, Aberdeen
Quantitative and in situ studies of human herpesvirus 6 in multiple sclerosis brain tissue	Dr DA Clark	Royal Free & Uinv. Coll. Med. School
Integrin signalling during oligodendrocyte differentiation	ffrench-Constant, Professor C	Cambridge University
Chemokine production and function by cells of the adult human nervous system	Professor DK Male	Open University
Axonal Injury and Disability in Multiple Sclerosis	Professor PM Matthews	Oxford University
Effects of Inflammation on Conduction in Normal and Demyelinated Central Axons	Professor KJ Smith	King's College, London
The role of chemokines and their receptors in the pathogenesis of multiple sclerosis	Dr MN Woodroofe	Sheffield Hallam University
Are T cell epitope spread and Th1 cytokine responses essential for relapsing and remitting EAE?	Dr DM Altmann	Imperial College, London
In vivo effects of fibroblast growth factor on oligodendrocytes and myelination	Dr AM Butt	King's College, London
An in vitro study of the role of matrix metalloproteinase and chemokines in CNS inflammation	Dr MN Woodroofe	Sheffield Hallam University
Virus induced apoptosis of glial cells	Dr JK Fazakerley	University of Edinburgh
HLA class II/human anti-MBP T cell receptor transgenics: T cell selection, disease protection and repair	Dr DM Altmann	Imperial College, London
A role for transforming growth factor beta1 in neuritogenesis and myelinogenesis in macrophage-enriched CNS aggregate cultures: implications for MS	Dr L Diemel	Institute of Neurology, London
The biology, behaviour and myelinating potential of immortalised cells of the adult human oligodendrocyte lineage	Dr NJ Scolding	Bristol University
Control of relapsing disease in models of MS	Dr D Baker	Institute of Neurology, London
Axo-oligodendroglial signals to promote remyelination	Dr L Wrabetz	H San Raffaele, Milan, Italy
A trial of intravesical atropine for detrusor hyperreflexia in multiple sclerosis	Professor JG Malone-Lee	UCL, London
Rehabilitation of Multiple Sclerosis	Dr Deirdre Walsh	Ulster University
MS Society Senior Research Fellowship in Scotland	Professor P Kennedy	Glasgow University
MS Society Senior Research Fellowship in Scotland	Professor S D Logan	University of Aberdeen
Restoration of conduction to demyelinated axons: a new pharmacological opportunity	Professor KJ Smith	King's College, London
Assessment and enhancement of the myelination of transplanted glial cell populations	Professor C ffrench-Constant	Cambridge University Centre for Brain Repair
The relative effectiveness of information, social support and psychological therapy for enhanced coping in MS	Dr CA Young	Walton Centre for Neurology & Neurosurgery
Gene therapy by expression of complement regulators in experimental models of demyelination	Professor BP Morgan	University of Wales, Cardiff
An exploratory study into the perceptions people with multiple sclerosis have of wheelchairs	Dr M Rice-Oxley	St. Richard's Hospital, Chichester
Schwann cell remyelination in the CNS: are the Schwann cells generated from CNS precurser?	Professor WF Blakemore	Cambridge University
Multiple sclerosis, MHC and NK receptor genes	Professor J Trowsdale	Cambridge University
Comprehensive analysis of autoreactive T cells in multiple sclerosis	Dr B Jakobsen	John Radcliffe Hospital, Oxford
Dendritic cells in acute and immune mediated lesions in the CNS	Professor VH Perry	Southampton University
Role of impulse activity in axonal degeneration in inflammatory demyelinating disease	Professor KJ Smith	King's College, London
Do Schwann cell precursors have favourable properties for myelin repair in the CNS? A study using drug- and immune-mediated models and myelin mutants.	Professor Jessen KR	UCL, London
Temporal appearance and pathogenic role of autoimmunity to myelin oligodendrocyte glycoprotein in the perpetuation and progression of experimental demyelinating disease and MS Principal grantholder	Dr S Amor	Imperial College, London
Alpha V integrin function during myelination	Professor C ffrench-Constant	Cambridge University
Cannabinoids in Multiple Sclerosis	Professor AJ Thompson	Institute of Neurology, London
The effects of cannabinoids on lower urinary tract symptoms and detrusor hyperreflexia in patients with MS: A multicentre, randomised, double blind controlled trial. (CAMS LUTS)	Mr RM Freeman	Derriford Hospital
Multiple Sclerosis in Northern Ireland - Do needs and provision correspond for patients and carers?	Professor PM Reilly	Queen's University, Belfast
The relationship between psycho/social adaptation to multiple sclerosis and coping responses when entering long term residential care	Ms Sheila Flynn	John Grooms
Management of the diagnostic phase of MS - a comparison of three models	Ms Bernadette Porter	Institute of Neurology, London
Randomised controlled trial of a patient-specific information handbook for use within a multidisciplinary Multiple Sclerosis clinic	Dr Mike Boggild	Walton Centre for Neurology & Neurosurgery
A pilot study to evaluate the impact of an education programme on people newly diagnosed with multiple sclerosis	Ms Jane Petty	Royal Hallamshire Hospital
Identification of cellular and molecular alterations in MS that may affect remyelination.	Professor R Reynolds	Imperial College, London
Multiple Sclerosis Impact Scale (MSIS-29) : Evaluation of responsiveness in hospital-based samples	Dr Jeremy Hobart	Institute of Neurology, London
Grant title Role of AP-1 and its possible target Mayven, in oligodendrocyte process formation	Dr SC Barnett	Glasgow University
Reflexology treatments for people with multiple sclerosis: a controlled study	Dr K Booth	Manchester University
Do chemokines contribute to blood-brain barrier dysfunction in multiple sclerosis? An in vitro study on astrocytes and brain endothelial cells.	Dr IA Romero	Open University
The effects of omega-6 fatty acid supplementation on membrane fatty acid composition and cytokines in relapse-remitting multiple sclerosis	Dr LS Harbige	University of Greenwich
Transcutaneous Electrical Nerve Stimulation : Is it effective in reducing spasticity in Multiple Sclerosis ?	Mrs LJ Miller	Ayrshire Central Hospital
Evaluation of Respite Care: MS Society	Dr I Smith	Nuffield Institute for Health
Evaluation of Respite Care: Definition of respite care in the UK; Description of MS Homes; National Policy; Mapping.	Mrs RA Chesson	Robert Gordon University, Aberdeen
Genetic Analysis of Multiple Sclerosis in EuropeanS (G.A.M.E.S.)	Professor DAS Compston	Cambridge University
Descriptive Studies of MS Society Homes in Scotland	Mrs RA Chesson	Robert Gordon University, Aberdeen