More MS news articles for Nov 2001

Onset of multiple sclerosis associated with anti-TNF therapy

Neurology 2001;57:1885-1888
Nancy L. Sicotte, MD and Rhonda R. Voskuhl, MD
From the Division of Brain Mapping (Dr. Sicotte), Department of Neurology (Drs. Sicotte and Voskuhl), UCLA School of Medicine, Los Angeles, CA.

Brief Communications

Therapies aimed at inhibiting tumor necrosis factor (TNF), a proinflammatory cytokine implicated in autoimmune disease are effective, especially for rheumatoid arthritis.

We report a patient with new onset MS closely associated with the initiation of anti-TNF therapy for juvenile rheumatoid arthritis.

It is possible that the inhibition of TNF triggered MS in this individual.

© 2001 American Academy of Neurology