More MS news articles for Nov 2001

Association of human herpesvirus 6 and human herpesvirus 7 with demyelinating diseases of the nervous system

J Neurovirol 2001 Dec;7(6):564-9 Books
Tomsone V, Logina I, Millers A, Chapenko S, Kozireva S, Murovska M.
August Kirchenshtein Institute of Microbiology and Virology, University of Latvia, Riga, Latvia.

Peripheral blood mononuclear cells and plasma of 113 patients with neurological disorders and 150 blood donors were analyzed for HHV-6 and HHV-7 sequences by PCR.

The prevalence of HHV-6 was significantly higher in patients with multiple sclerosis (P < 0.01) than in cases of nondemyelinating diseases of the central and demyelinating diseases of the peripheral nervous systems and blood donors.

HHV-6 viremia was found only in patients with multiple sclerosis, predominantly in the active phase of the disease.

A significantly higher frequency of HHV-7 reactivation in patients with demyelinating diseases of the peripheral nervous system suggests also its association with demyelinating processes.

PMID: 11704889 [PubMed - in process]