J Neurovirol 2001 Dec;7(6):493-500
Karpus WJ.
Department of Pathology, Northwestern
University Medical School, Chicago, Illinois, USA.
Chemokines and their receptors are large families of inflammatory molecules responsible for a number of biologic functions including the accumulation of leukocytes at tissue sites.
Over the past 8 years, a number of studies have indicated a role for chemokines in the pathogenesis of CNS inflammatory diseases.
This minireview provides a brief
summary of our current knowledge of chemokines and CNS inflammatory diseases
including experimental autoimmune encephalomyelitis, multiple sclerosis,
virus-induced demyelinating diseases, Alzheimer's disease, and central
nervous system bacterial-induced diseases.
PMID: 11704881 [PubMed - in process]