More MS news articles for Nov 2001

Chemokines and central nervous system disorders

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11704881&dopt=Abstract

J Neurovirol 2001 Dec;7(6):493-500
Karpus WJ.
Department of Pathology, Northwestern University Medical School, Chicago, Illinois, USA.

Chemokines and their receptors are large families of inflammatory molecules responsible for a number of biologic functions including the accumulation of leukocytes at tissue sites.

Over the past 8 years, a number of studies have indicated a role for chemokines in the pathogenesis of CNS inflammatory diseases.

This minireview provides a brief summary of our current knowledge of chemokines and CNS inflammatory diseases including experimental autoimmune encephalomyelitis, multiple sclerosis, virus-induced demyelinating diseases, Alzheimer's disease, and central nervous system bacterial-induced diseases.
 

PMID: 11704881 [PubMed - in process]