Nov. 9, 2001 (Ivanhoe Newswire) — Researchers now believe adult bone marrow cells have characteristics similar to embryonic stem cells and may be an excellent source of cells for future research and therapy.
The study, conducted by the University of Minnesota Stem Cell Institute (SCI), demonstrated the isolation and expansion of cells derived from adult healthy human bone marrow. In fact, the adult stem cell population was shown to be able to expand for more than 50 populations without obvious signs of differentiation or aging. It can also be readily changed to another line.
Stem cells have been identified in most organ tissues, including neural, gastrointestinal, epidermal and hepatic. The results, say researchers, clearly show the potential of these adult bone marrow stem cells to differentiate cells into cells such as those that line body cavities. The cells may also be able to differentiate into nerve cells.
Researchers say the potential future use of adult stem cells may have huge implications for therapy of degenerative or traumatic disorders like osteoporosis, arthritis and vascular problems, or for therapy of singe gene disorders like hemophilia and muscular dystrophy. Additional research on the long-term viability of adult stem cells may lead to better sources of stem cells for gene therapy of congenital disorders characterized by enzyme deficiencies, including Gaucher disease and leukodystrophies.
SOURCE: Blood, 2001;90:2613-2623
Copyright © 2001 Ivanhoe Broadcast
Copyright © 2001 Ivanhoe Broadcast News, Inc