More MS news articles for May 2004

Alpha Lipoic Acid may inhibit T-Cell migration into Spinal Cord

http://www.bostoncure.org:8080/article.pl?sid=04/05/20/1158228&mode=nested

May 20th, 2004
Scott
Boston Cure Project

Two reports from the recent American Academy of Neurology show researchers looking into the effects of a common nutritional supplement, Alpha-Lipoic Acid. ALA suppresses EAE by inhibiting T cell migration into the spinal cord and does so partly by inhibiting matrix metalloproteinase-9 (MMP-9) activity. Effective dosage appeared to be at 1200 mg/day; at 600 mg/day, there was no increase in the serum blood level of ALA. Abstracts on the two studies are here and here.