Medical Matters - 05/01/03 - 10 p.m. report
By: Marsha Thompson
Multiple Sclerosis is the most common neurological disorder in young adults - especially women. It can lead to devastating disability... And there's no cure. But now doctors have a new weapon in the battle against MS "Follow my finger around with your eyes." Stacey Hughes was diagnosed with Multiple Sclerosis after she started losing vision in her left eye. Stacey,"You walk out of the office with this diagnosis and you think oh my gosh and you have to go find a way to make it work with your world." In Multiple Sclerosis ... Immune cells that normally protect the body attack healthy brain tissue. The cells move through the blood-brain barrier into the brain. That triggers inflammation that ultimately destroys nerves, such as the optic nerve. "These are the areas of inflammation that will ultimately end us as ms plaque. " Now Neurologists are testing a new MS therapy called Antegren.
Antegren - shown here in yellow - binds to a specific molecule on the immune cell surface. This keeps the immune cell from leaving the bloodstream and moving into the brain. J. Theodore Phillips, M.D., Ph.D., Dir., MS Research Center, Texas neurology "If we can block that process than we ought to be able to benefit the disease." A study published in the New England Journal of Medicine found, antegren slashed the number of new inflammatory sites - called brain lesions - by 93 percent. "It is effective in a way that may in fact surpass any of our other treatment options." Stacey volunteered for the study. A recent MRI showed she had no new or active lesions. "I felt a whole lot better, really quickly within like the first six weeks I had lost all the numbness and tingling in my legs and I just generally felt a better sense of well-being." "Knock on wood everything's great."
For Crohn's disease trials:888-635-6243 Antegren is currently in advanced clinical trials... You can find out how to participate by calling 888-456-2255. Researchers are also using it to treat Crohn's disease.
Here's a little history for you -- MS was among the first diseases to
be described scientifically. The National Multiple Sclerosis Society says
doctors did not understand what they saw and recorded, but medical drawings
done as early as 1838 clearly show what we today recognize as MS.
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