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More MS news articles for March 2004

Phanerogenetic retrocochlear low frequency hearing loss

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15040112

Zhonghua Er Bi Yan Hou Ke Za Zhi. 2003 Dec;38(6):459-64
Han WJ, Gu R, Yu LM, Zheng JF, Zhou N, Cao JY, Wang L.
Department of Otorhinolaryngology and Head & Neck Surgery, General Hospital of PLA, Beijing 100853, China.

OBJECTIVE:

To study the pathogenisis of retrocochlear low frequency hearing loss.

METHODS:

Clinical and audiologic findings [auditory brainstem response (ABR), evoked otoacoustic emission (EOAE), et al] of 29 cases with retrocochlear low frequency hearing loss were studied.

RESULTS:

The head injury, acoustic neuroma, peripheral neurophathy, hereditary hear loss, multiple sclerosis and brainstem disease can cause retrocochlear low frequency hearing loss.

The typical clinical manifestations of retrocochlear low frequency hearing loss were normal EOAE which cannot be suppressed by contralateral white noise, but with abnormal ABR as well as with no acoustic reflex and -SP/AP > 0.44.

CONCLUSIONS:

The results suggest that phanerogenetic retrocochlear low frequency hearing loss should be a syndrome rather than a disease called "auditory neuropathy".

The main lesions of the disease are brainstem, cochlear nuclei and auditory nerve.