Feb 26, 2003
Nearly all patients with progressive multiple sclerosis, a more advanced form of the disease, have a particular antibody in their blood, according to study findings presented at the 127th annual meeting of the American Neurological Association.
Researchers examined antibodies that bind to a component of the myelin known as myelin oligodendrocyte glycoprotein (MOG).
The study involved 27 patients who had relapsing-remitting MS, 49 who had progressive MS and 18 healthy individuals who were examined for the presence of several anti-myelin antibodies, including anti-MOG.
Approximately 33 percent of healthy people and patients with the relapsing-remitting MS tested positive for anti-MOG. In contrast, anti-MOG was found in the blood of nearly all patients with progressive multiple sclerosis. Other anti-myelin antibodies were equally common among the three groups.
For MS, there are few markers for disease progression, researchers noted. Now, we have a blood test that may provide an indication of disease progression. Larger studies are needed to confirm the current findings, but still it's a very exciting prospect.
© FWI 2003