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More MS news articles for March 2003

Personality traits in multiple sclerosis (MS) patients with and without fatigue experience

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12614312&dopt=Abstract

Acta Neurol Scand 2003 Mar;107(3):195-201
Merkelbach S, Konig J, Sittinger H.
Department of Neurology, Institute of Medical Biometrics, Epidemiology and Medical Informatics, and Department of Psychiatry, Saarland University, D-66421 Homburg/Saar, Germany.

OBJECTIVES -:

To determine the impact of personality characteristics on feelings of fatigue in multiple sclerosis (MS) patients and to compare the results with the impact of bodily impairment.

PATIENTS AND METHODS -:

Eighty patients with definite MS (mean age 38.5 +/- 9.0 years, 62 females) were surveyed using questionnaires assessing fatigue experience and personality traits (German Freiburg Personality Inventory-Revised; FPI-R) and by clinical examination assessing the Expanded Disability Status Scale.

RESULTS -:

Increased levels of "neuroticism", and "excitability" and decreased levels of "extraversion" were found to relate independent of fatigue scores (0.21 < beta < 0.52; 0.05 < P < 0.0001).

The impact of these personality traits on fatigue (partial R2 ranging up to 0.32; 0.02 < P < 0.0001) was much higher than the impact of physical impairment (partial R2 ranging up to 0.04; not significant).

CONCLUSION -:

Our results support a psychological model of fatigue in MS.

FPI-R-items over-weighted somatic sources of the fatigue syndrome in MS and may specifically relate to fatigue experience in chronical disorders.