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More MS news articles for June 2004

Overview of European pilot study of interferon ß-1b in primary progressive multiple sclerosis

Multiple Sclerosis 15 June 2004, vol. 10, no. Supplement 1, pp. 62-64(3)
Montalban X.
University Hospital Vall d'Hebron, Unitat de Neuroimmunologia Clinica, E-08035, Barcelona, Spain

This short monograph describes a trial of interferon ß-1b in patients with primary progressive multiple sclerosis (PPMS) or transitional MS.

Designed as a randomized, placebo-controlled pilot, the trial randomly placed 73 eligible patients into two groups, placebo or interferon ß-1b 8 MIU given subcutaneously every other day for two years.

Significant differences favouring interferon ß-1b in the MSFC score, T2 lesion volume and T1 lesion volume at 24 months were observed.

Further study of interferon ß-1b therapy in PPMS patients is warranted.