All About Multiple Sclerosis

More MS news articles for June 2003

Is natalizumab a breakthrough in the treatment of multiple sclerosis?

Expert Opin Pharmacother. 2003 Jun;4(6):999-1001
Doggrell SA.
School of Biomedical Sciences, The University of Queensland, QLD 4072, Australia.

In patients with either relapsing-remitting or secondary-progressive multiple sclerosis, there were fewer new lesions/patient with natalizumab (0.7 and 1.1 with natalizumab 3 and 6 mg/kg every 28 days, respectively) than in the placebo group (9.6 new lesions/patient) over 6 months.

There were also fewer relapses in the natalizumab groups than the placebo group.

However, there were no changes in the Expanded Disability Status Scale scores in any of the groups.

Natalizumab was well-tolerated.

Thus, the initial results with natalizumab treatment over 6 months in multiple sclerosis are encouraging.