All About Multiple Sclerosis

More MS news articles for June 2003

Anesthetic management for a patient with multiple sclerosis at exacerbation stage under general anesthesia

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12795136&dopt=Abstract

Masui. 2003 May;52(5):521-3
Yamashita K, Yokoyama T, Tokai H, Imazu Y, Lee M, Manabe M.
Department of Anesthesiology and Resuscitology, Kochi Medical School, Nankoku 783-8505.

A 39-year-old woman with multiple sclerosis (MS) at exacerbation stage underwent dilatation and curettage.

MS is characterized by chronic inflammation, demyelination, and gliosis in the central nervous system.

Surgical stress often induces exacerbation of MS symptoms.

Therefore, deep anesthesia is required for anesthetic management in cases of MS.

We monitored electroencephalograph (EEG), spectral edge frequency 90 (SEF 90), spectral median frequency (SMF) and delta-amplitude for depth of anesthesia using pEEG (Drager, Germany).

In this case, anesthesia was induced with sevoflurane and gradually increased to 5% in oxygen 4 l.min-1 and maintained with sevoflurane 2-3% in 2 nitrous oxide l.min-1 and 2 l.min-1 oxygen.

Surgery was completed and no spike wave was observed by pEEG monitoring during surgery.

In conclusion, sevoflurane anesthesia was useful for a patient with MS during exacerbation stage.