Rev Neurol (Paris) 2003 May;159(5 Pt 1):571-3
Gaudez C, Regnier S, Aractingi S, Heinzlef O.
Service de Dermatologie.
We report the first case of a 33-year-old woman with multiple sclerosis, who developed a livedo-like dermatitis after injection of Copolymer-1.
This disease is characterized by the development of acute violent pain during or immediatly after injection, and a livedo-like plaque followed by necrosis corresponding to an arterial ischemia by vasospasm or thrombosis.
Early treatment with vasoactive and anticoagulation agents is required.
Surgery may be necessary.