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More MS news articles for July 2003

Spatial vision in visually asymptomatic subjects at high risk for multiple sclerosis

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12876258&dopt=Abstract

J Neurol Neurosurg Psychiatry. 2003 Aug;74(8):1145-7
Frisen L.
Institute of Clinical Neuroscience, Sahlgren's Academy of Goteborg University, Sweden.

OBJECTIVE:

To investigate the state of spatial vision in visually asymptomatic subjects at high risk for multiple sclerosis.

METHODS:

Fifteen subjects suffering a first neurological episode suggestive of multiple sclerosis in clinical presentation, immunological profile, and magnetic resonance imaging, were examined with a new, sensitive test of spatial vision, rarebit perimetry.

None had symptoms or signs of optic neuropathy.

RESULTS:

Results of rarebit perimetry were significantly worse than those of 15 age matched normal controls (p=0.01); seven patients (47%) were outside normal limits.

One patient only obtained abnormal results in high pass resolution perimetry.

CONCLUSIONS:

Rarebit perimetry may help to close the sensitivity gap between clinical examinations and neuroimaging.