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More MS news articles for February 2003

Clinical exacerbation of multiple sclerosis following radiotherapy

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12580715&dopt=Abstract

Arch Neurol 2003 Feb;60(2):273-5
Murphy CB, Hashimoto SA, Graeb D, Thiessen BA.
Division of Neurology, British Columbia Cancer Agency, Department of Medical Oncology, 600 W 10th Ave, Vancouver, British Columbia V5Z 4E6, Canada.

BACKGROUND:

Radiation of the central nervous system in patients with demyelinating disease may have deleterious effects.

OBJECTIVE:

To describe a 30-year-old woman with multiple sclerosis who developed an attack of demyelination 2 months following radiotherapy for a parotid malignancy.

RESULTS:

Magnetic resonance imaging demonstrated new hyperintense lesions that corresponded to both the localization of the patient's symptoms and to the area defined by the 50% isodose radiation field.

CONCLUSION:

Radiation treatment likely triggered an exacerbation of multiple sclerosis.