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More MS news articles for February 2003

Autoimmune neutropenia associated with multiple sclerosis

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12583629&dopt=Abstract

Intern Med 2003 Jan;42(1):102-4
Kozuka T, Kojima K, Kaneda K, Takenaka K, Manabe Y, Hirata Y, Okuma S, Toki H, Tanimoto M.
Department of Internal Medicine II, Okayama University Medical School, Okayama.

A 53-year-old Japanese man with multiple sclerosis developed autoimmune neutropenia.

The neutrophil count was consistently less than 0.2 x 10(9)/l, irrespective of the disease activity of multiple sclerosis or the administration of immunosuppressive agents or granulocyte colony-stimulating factor.

After high-dose gamma-globulin therapy was started, temporary increases in the neutrophil count were observed.

Despite a wide spectrum of clinical manifestations in multiple sclerosis, autoimmune neutropenia has never been reported previously.