Clin Neuropathol. 2003 Nov-Dec;22(6):304-8
Shuangshoti S, Hjardermaal GM, Ahmad Y, Arden JL, Herman MM.
Department of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
We report a 39-year-old female patient known to have multiple sclerosis (MS), who later developed cerebral glioblastoma.
The tumor was documented on the brain-magnetic resonance imaging (MRI) during the work-up for an apparent relapsing MS, and was subsequently confirmed pathologically by stereotactic biopsy and the postmortem brain examination.
Our case, as well as others, re-emphasizes the need to evaluate the symptoms and brain MRI carefully, even in well-documented MS subjects.
The concurrence of MS and intracranial glioma is uncommon.
The possible relationship between the 2 diseases was discussed, and related literature reviewed.