More MS news articles for Dec 2001

Optic neuritis: differential diagnosis

Online publication: December 5, 2001
Neurological Sciences
Abstract Volume 22 Issue 8 (2001) pp S52-S54
S. Bianchi Marzoli (1), V. Martinelli (2)
(1) Neuro-Ophthalomology Unit, Department of Ophthalmology, H S Raffaele Scientific Institute, Vita-Salute University School of Medicine, Via Olgettina 60, I-20123 Milan, Italy
(2) Department of Neurology, H S. Raffaele Scientific Institute, Vita-Salute University School of Medicine, Milan, Italy


Optic neuritis can be mimicked by other optic neuropathies and by anterior segment, choroidal or retinal diseases.

Retinal diseases may cause central visual loss when they involve the macular or peripapillary area.

Central serous retinopathy, hereditary retinal diseases, white dots syndromes and autoimmune retinopathies may present a clinical picture similar to that of optic neuritis.

Complete neuro-ophthalmological examination must be performed to differentiate optic nerve damage from other ocular structures involvement.

As in optic neuritis, optic disc and macula appearance may be completely normal in several retinal diseases.

Fluorescein aniography and electrophysiological testing are relevant for the differential diagnosis in many challenging cases.

© Springer-Verlag Italia 2001