More MS news articles for Dec 2001

The immunological basis of current and novel therapies of multiple sclerosis

Arch Immunol Ther Exp (Warsz) 1999;47(1):7-16
Dubois B, Opdenakker G.
Rega Institute for Medical Research, Laboratory of Molecular Immunology, University of Leuven, Belgium.

The etiology and the pathogenesis of multiple sclerosis are not yet known.

There might be a role for genetic susceptibility, for environmental factors and for inflammatory and immunological changes.

Most of the actual therapies are based on the latter two phenomena.

We review here corticosteroids, interferon beta and copolymer 1 as the current drugs of choice and compare schematically the immunological basis of the mechanisms of action of these three substances with those of experimental or other treatments.

PMID: 11729832 [PubMed - in process]