More MS news articles for Dec 2001

Most MS patients with seizures respond to drug therapy, study shows

Most MS patients who have seizures can be effectively treated with antiepileptic drugs, researchers reported.

Investigators reviewed medical records of 5,715 MS patients seen at the Mayo Clinic in Rochester, Minn., between 1990 and 1998. Of those patients, 51 experienced at least one seizure.

Among patients who had a seizure, 35 percent experienced only one episode.

The most common condition was generalized tonic-clonic seizure, which occurred in 69 percent of the patients. Approximately 22 percent had simple or complex partial seizures.

In 37 of the 51 patients, or 73 percent, the patient’s first seizure came after that patient was diagnosed with MS.

Of the 45 patients who received antiepileptic drugs, 78 percent had no more seizures after the initiation of treatment. Eleven percent had a seizure disorder that was incurable or resistant to treatment.

“Most of the patients with MS who experienced seizure activity had a benign and transient disorder that was responsive to AED treatment or required no therapy,” the researchers concluded.

Results of the study appear in the October issue of Mayo Clinic Proceedings.

© 2001 Spotlight Health