Int MS J. 2003 Apr;10(1):2-4
Kerschensteiner M, Hohlfeld R.
Brain Research Institute, University of Zurich, Switzerland.
Multiple sclerosis (MS) is the most common inflammatory, demyelinating disease of the central nervous system (CNS).
Although the traditional belief is that MS is caused by an autoimmune reaction to myelin antigens, evidence now suggests that the target is the entire myelin-axonal unit, rather than just myelin.
The disruption of myelin and axons leads to persistent neurological deficits.