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More MS news articles for August 2003

Genome-wide scanning for susceptibility genes in researches on six HLA-associated diseases

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2003 Aug 10;20(4):336-41
Gu M, Wang Z, Huang W, Fan L.
Department of Medical Genetics, Shanghai Second Medical University, Shanghai, 200025 P.R.China

Six human leucocytic antigen(HLA)-associated diseases, including ankylosing spondylitis, rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, type 1 diabetes mellitus and psoriasis, were selected as objects of this review.

The characteristics of these diseases in whole-genome scans on susceptibility genes or loci undertaken to date were analyzed and compared.

Meanwhile, the potential proposals for dealing with the existing problems were put forward.