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More MS news articles for August 2003

Autoimmune optic neuropathy with anticardiolipin antibody mimicking multiple sclerosis in a child

Am J Ophthalmol. 2003 Aug;136(2):358-60
Frohman L, Turbin R, Bielory L, Wolansky L, Lambert WC, Cook S.
Department of Ophthalmology, University of Medicine and Dentistry New Jersey, New Jersey Medical School, Newark, New Jersey, USA


To demonstrate that autoimmune optic neuropathy (AON) may occur in the pediatric population.


Interventional case report.


A 4-year-old developed four episodes of bilateral optic neuritis with mild concurrent weakness, ataxia, or dizziness; one episode of unilateral optic neuritis; and one episode of weakness over a period of 4 years.


Autoimmune optic neuropathy was diagnosed because of the presence of anticardiolipin antibody and an abnormal skin biopsy with thrombin and immunoreactant deposition.

She was treated with corticosteroids, aspirin, and gammaglobulin.

This diminished the frequency and intensity of her attacks.


This case represents the diagnosis and treatment of AON in a child.