More MS news articles for August 2002

Increased post-exercise facilitation of motor evoked potentials in multiple sclerosis

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12140010&dopt=Abstract

Clin Neurophysiol 2002 Aug;113(8):1295-1300
Nielsen JF, Norgaard P.
Department of Neurology, Aarhus University Hospital, Norrebrogade 44, 8000, Aarhus, Denmark

OBJECTIVES:

To study post-exercise facilitation following a non-fatigue exercise in a homogenous group of multiple sclerosis (MS) patients with complaints of muscle fatigue.

METHODS:

In 15 MS patients and matched controls motor evoked potentials (MEP) were recorded from the biceps brachii muscle at time delays of 0.5-30s after an isometric contraction with a torque of 50% of maximal voluntary contraction (MVC) maintained for 2-6s. In addition, MEP was recorded after isometric torque of 25, 50, and 100% of MVC maintained for 6s.

RESULTS:

Isometric non-fatigue contraction induced significant post-exercise increase in MEP amplitude in MS patients compared with controls being most pronounced after a contraction for 6s. The post-exercise increase in MEP lasted for longer than 30s in MS patients.

CONCLUSIONS:

Post-exercise increase of MEP amplitude following a non-fatigue exercise was significant in MS patients with complaints of muscle fatigue compared with healthy subjects.