Immunity 2002 Jul;17(1):1-6
Liblau RS, Wong FS, Mars LT, Santamaria P.
INSERM U563 and Immunology Laboratory, Toulouse University Hospital, France
The importance of CD8 T cells in the pathogenesis of organ-specific autoimmune diseases has not previously been well recognized.
Recent evidence, however, indicates that autoreactive CD8 T cells can contribute substantially to tissue damage in both murine and human autoimmune disorders.
As such, these T cells now become an attractive target for therapeutic intervention.