More MS news articles for August 2002

Chart of the Disease-Modifying Drugs

http://www.nationalmssociety.org/IMSSu02-RebifChart.asp

InsideMS; Summer 2002; Vol. 20, Issue 3
 
Brand and Generic Name
Avonex Interferon Beta-1a
Betaseron Interferon Beta-1b
Copaxone Glatiramer Acetate
Rebif Interferon Beta-1a
Manufacturer/Distributor/When Approved
Avonex Biogen
1996 (May)
Betaseron Berlex
1993
Copaxone Teva Pharmaceutical Industries
1996 (December)
Rebif Serono, Inc.
2002 (March)
How Often/How/Common Side Effects
Avonex
  • Weekly; intramuscular (into the muscle) injection.
  • Flu symptoms following injection, which lessen over time for many people. Rarer: mild anemia, elevated liver enzymes.
Betaseron
  • Every other day; subcutaneous (under the skin) injection
  • Flu symptoms following injection, which lessen over time for many. Injection site reactions, about 5% of which need medical attention. Rarer: elevated liver enzymes, low white blood cell counts.
Copaxone
  • Daily; subcutaneous (under the skin) injection
  • Injection site reactions. Rarer: a reaction immediately after injection, which includes anxiety, chest tightness, shortness of breath, and flushing. This lasts 1530 minutes and has no known long-term effects.
Rebif
  • Three times a week; subcutaneous (under the skin) injection
  • Flu-like symptoms following injection, which lessen over time for many. Injection site reactions. Less common: Abnormalities of liver function and decreases in red or white blood cell counts.
Approximate Retail Cost Per Year
Avonex $10,412
Betaseron $12,544
Copaxone $11,280
Rebif $13,875
(source: www.drugstore.com as of May 2002)
For Information and Financial Support
Avonex Avonex Alliance
800-456-2255
http://www.avonex.com
Betaseron Pathways
800-788-1467
http://www.betaseron.com
Copaxone Shared Solutions
800-887-8100
http://www.copaxone.com
Rebif MS LifeLines
877-44-REBIF
http://www.rebif.com

© 2002 The National Multiple Sclerosis Society