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More MS news articles for April 2003

Magnetization transfer imaging techniques in understanding the various characteristics of multiple sclerosis

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12690734&dopt=Abstract

Rev Neurol (Paris) 2002 Dec;158(12 Pt 1):1157-73
Grimaud J, Zhou LQ, Zhu YM.
Centre de Recherche et d'Applications en Traitement de l'Image et du Signal (CREATIS), UMR CNRS 5515, INSA-Lyon.

The purpose of this review of the literature is to analyze the contribution of magnetization transfer (MT) imaging techniques in understanding the various characteristics of multiple sclerosis.

MT imaging allows contrast augmentation by use of magnetization transfer contrast.

MT imaging allows lesion characterization by means of quantification of the degree of signal loss due to magnetization transfer contrast by a magnetization transfer ratio.

It is used as an indicator of tissue destruction; in particular, to demyelination.

Both applications of MT imaging in multiple sclerosis are studied in this review, as well as the methodological and technical limitations.