Comments for All About Multiple Sclerosis - The Blog http://www.mult-sclerosis.org/blog Mon, 27 Feb 2012 12:26:00 +0000 hourly 1 http://wordpress.org/?v=3.2.1 Comment on Is Multiple Sclerosis an Autoimmune Disease? by Stingoali http://www.mult-sclerosis.org/blog/?p=145#comment-768 Stingoali Mon, 27 Feb 2012 12:26:00 +0000 http://www.mult-sclerosis.org/blog/?p=145#comment-768 http://www.youtube.com/watch?v=KShwMw5ehHw&feature=channel_video_title MS has a venodynamic origin visible on MRI The size of the worldwide MS drugs market which is expected to reach $20.2 billion annually, by 2017. http://www.companiesandmarkets.com/Market/Healthcare-and-Medical/Market-Research/Multiple-Sclerosis-Therapeutics-Pipeline-Assessment-and-Market-Forecasts-to-2017/RPT834651 People with MS are not 'people' to the pharmaceutical industry – we are 'the MS market'. As it says in the report above “identify, understand, capitalise”. According to Tan et al With MR venography, the perivenous distribution of MS lesions in the brain can be visualized in vivo. The venous anatomy defines the typical form and orientation of these lesions”. there is no chance of the MS Society replying to your reasonable enquiry because they are ground troops for the pharmaceutical industry. see pages 74 and 76 best get your vascular/venous system checked out (CCSVI) http://www.youtube.com/watch?v=KShwMw5ehHw&feature=channel_video_title

MS has a venodynamic origin visible on MRI

The size of the worldwide MS drugs market which is expected to reach $20.2 billion annually, by 2017.

http://www.companiesandmarkets.com/Market/Healthcare-and-Medical/Market-Research/Multiple-Sclerosis-Therapeutics-Pipeline-Assessment-and-Market-Forecasts-to-2017/RPT834651

People with MS are not ‘people’ to the pharmaceutical industry – we are ‘the MS market’. As it says in the report above “identify, understand, capitalise”.

According to Tan et al
With MR venography, the perivenous distribution of MS lesions in the brain can be visualized in vivo. The venous anatomy defines the typical form and orientation of these lesions”.

there is no chance of the MS Society replying to your reasonable enquiry because they are ground troops for the pharmaceutical industry.
see pages 74 and 76

best get your vascular/venous system checked out (CCSVI)

]]> Comment on Coming to terms with Secondary Progressive MS by Sharon Rainbird http://www.mult-sclerosis.org/blog/?p=51#comment-521 Sharon Rainbird Thu, 12 Jan 2012 23:17:16 +0000 http://www.mult-sclerosis.org/blog/?p=51#comment-521 You have an amazing attitude towards your MS. I admire you very much. It was heartbreaking to read your blog, but at the same time, very motivating. I too, have MS with an apparently bad prognosis by my Neurologist. I hope I have your attitude when (if) the time comes. I will remember to try and replace loss with something new. I wish you all the best. You have an amazing attitude towards your MS. I admire you very much. It was heartbreaking to read your blog, but at the same time, very motivating. I too, have MS with an apparently bad prognosis by my Neurologist. I hope I have your attitude when (if) the time comes. I will remember to try and replace loss with something new.
I wish you all the best.

]]> Comment on Is Multiple Sclerosis an Autoimmune Disease? by Omar Ochoa http://www.mult-sclerosis.org/blog/?p=145#comment-404 Omar Ochoa Wed, 21 Dec 2011 16:42:36 +0000 http://www.mult-sclerosis.org/blog/?p=145#comment-404 I'm a fitness intructor and the fitness world is clueless on how to properly train people with MS. My friend Roxana has MS and she was currently taking Copaxone, Excuse my spelling. Her doctor put her on Mitoxantrone. I heard its dangerous, however, I'm taking it upon myself to put more research of proper excersises for clients with MS. If anyone has any questions Feel free to ask. I’m a fitness intructor and the fitness world is clueless on how to properly train people with MS. My friend Roxana has MS and she was currently taking Copaxone, Excuse my spelling. Her doctor put her on Mitoxantrone. I heard its dangerous, however, I’m taking it upon myself to put more research of proper excersises for clients with MS. If anyone has any questions Feel free to ask.

]]> Comment on Is Multiple Sclerosis an Autoimmune Disease? by Lisa http://www.mult-sclerosis.org/blog/?p=145#comment-382 Lisa Sun, 18 Dec 2011 19:38:44 +0000 http://www.mult-sclerosis.org/blog/?p=145#comment-382 Please keep talking. This is highly interesting. Please keep talking. This is highly interesting.

]]> Comment on Is Multiple Sclerosis an Autoimmune Disease? by Craig Garrison http://www.mult-sclerosis.org/blog/?p=145#comment-352 Craig Garrison Thu, 15 Dec 2011 05:41:21 +0000 http://www.mult-sclerosis.org/blog/?p=145#comment-352 I'm going to highlight a couple of things from my Autologous Hemapoietic Stem Cell Transplant (AHSCT), but they probably don't shed any more light on the autoimmune or not debate. Still, it will be a look inside a treatment which works. AHSCT was thought to be a way to cut-off the autoimmune attacks at the source (bone marrow is the source of T-cells, a type of white blood cell). The idea was to take some of my stem cells from my marrow, clean them of any other blood cells, i.e., set aside a collection of stem cells in plasma, then kill my bone marrow so that I was no longer producing white blood cells. Then, they monitored my blood and waited for my white blood cell count to go to zero. At that point, I no longer had an adaptive immune system (and, that is why this procedure is dangerous). Then, I got my clean stem cells reinfused so that I could develop a new immune system which ideally would no longer attack myelin. A good plan to attack an autoimmune disease. But, it didn't work. After my new immune system developed, tests of my blood showed that I still had T-cells that were reactive to myelin. So, maybe MS isn't an autoimmune disease. But, it did work. Seven of us went through the trial at Methodist Hospital in Houston. After treatment, six no longer had exacerbations. (The seventh was the only primary progressive in the trial.) I haven't had an exacerbation in nearly ten years. So, maybe MS is an autoimmune disease, but T-cells are the wrong target. I read the paper published on the Houston results. Interleukin-12 (IL-12), an immune system signaling agent went to zero in all the patients. I pointed this out to the lead researcher, but for some reason, he was not comfortable with drawing what I thought was an obvious conclusion. Some time later, I read that Abbott Labs was trialing an anti-IL-12 monoclonal antibody. I haven't kept track of how that went. From my experience, MS may or may not be an autoimmune disease, but it can be halted by tinkering with the immune system. I’m going to highlight a couple of things from my Autologous Hemapoietic Stem Cell Transplant (AHSCT), but they probably don’t shed any more light on the autoimmune or not debate. Still, it will be a look inside a treatment which works.

AHSCT was thought to be a way to cut-off the autoimmune attacks at the source (bone marrow is the source of T-cells, a type of white blood cell). The idea was to take some of my stem cells from my marrow, clean them of any other blood cells, i.e., set aside a collection of stem cells in plasma, then kill my bone marrow so that I was no longer producing white blood cells. Then, they monitored my blood and waited for my white blood cell count to go to zero. At that point, I no longer had an adaptive immune system (and, that is why this procedure is dangerous). Then, I got my clean stem cells reinfused so that I could develop a new immune system which ideally would no longer attack myelin. A good plan to attack an autoimmune disease.

But, it didn’t work. After my new immune system developed, tests of my blood showed that I still had T-cells that were reactive to myelin. So, maybe MS isn’t an autoimmune disease.

But, it did work. Seven of us went through the trial at Methodist Hospital in Houston. After treatment, six no longer had exacerbations. (The seventh was the only primary progressive in the trial.) I haven’t had an exacerbation in nearly ten years. So, maybe MS is an autoimmune disease, but T-cells are the wrong target.

I read the paper published on the Houston results. Interleukin-12 (IL-12), an immune system signaling agent went to zero in all the patients. I pointed this out to the lead researcher, but for some reason, he was not comfortable with drawing what I thought was an obvious conclusion. Some time later, I read that Abbott Labs was trialing an anti-IL-12 monoclonal antibody. I haven’t kept track of how that went.

From my experience, MS may or may not be an autoimmune disease, but it can be halted by tinkering with the immune system.

]]> Comment on If Dreaming Were An Olympic Sport by Marilyn http://www.mult-sclerosis.org/blog/?p=158#comment-351 Marilyn Wed, 14 Dec 2011 13:22:52 +0000 http://www.mult-sclerosis.org/blog/?p=158#comment-351 Ah, yes. I used to dream I was running -- usually in high heels. I would just kind of float over the landscape. :-) Ah, yes. I used to dream I was running — usually in high heels. I would just kind of float over the landscape. :-)

]]> Comment on If Dreaming Were An Olympic Sport by Tick http://www.mult-sclerosis.org/blog/?p=158#comment-333 Tick Sat, 10 Dec 2011 00:41:28 +0000 http://www.mult-sclerosis.org/blog/?p=158#comment-333 I haven't been able to actually run for something like 20 years although I was walking fairly well up until about 5 years ago. I do dream of running though. That's a good thing. Many of those dreams I'm running in Vietnam, 40 some odd years ago. That's a bad thing. Occasionally I dream of rodeo events although I haven't done that for 30 years. I also dream of dancing sometimes. Nothing like a little Texas Two-Step to make you wake up with a smile on your face. I haven’t been able to actually run for something like 20 years although I was walking fairly well up until about 5 years ago.

I do dream of running though. That’s a good thing. Many of those dreams I’m running in Vietnam, 40 some odd years ago. That’s a bad thing.

Occasionally I dream of rodeo events although I haven’t done that for 30 years. I also dream of dancing sometimes. Nothing like a little Texas Two-Step to make you wake up with a smile on your face.

]]> Comment on If Dreaming Were An Olympic Sport by Jan Pruchnicki http://www.mult-sclerosis.org/blog/?p=158#comment-319 Jan Pruchnicki Tue, 06 Dec 2011 17:54:22 +0000 http://www.mult-sclerosis.org/blog/?p=158#comment-319 I've had the running dreams, too. There is probably an equal mix of remembrance and longing lodged in the subconscious and it manifests itself with these dreams. You are correct: They are lovely and the effort to run in them is so easy and natural. Then you wake up and reality hits you like a hammer. Maybe these dreams are a defense mechanism the mind uses to relieve the mental stress that comes with dealing with our daily reality. A special kind of escapism neurons, perhaps? I’ve had the running dreams, too. There is probably an equal mix of remembrance and longing lodged in the subconscious and it manifests itself with these dreams. You are correct: They are lovely and the effort to run in them is so easy and natural. Then you wake up and reality hits you like a hammer. Maybe these dreams are a defense mechanism the mind uses to relieve the mental stress that comes with dealing with our daily reality. A special kind of escapism neurons, perhaps?

]]> Comment on Coming to terms with Secondary Progressive MS by Jackie Martinez http://www.mult-sclerosis.org/blog/?p=51#comment-287 Jackie Martinez Fri, 25 Nov 2011 17:26:33 +0000 http://www.mult-sclerosis.org/blog/?p=51#comment-287 How do stay positive? Hoe does it not eat at you? I've become so bitter at times it's not funny and though I used be such a "fighter" I feel just tired of fighting. So how do you do it? How do stay positive? Hoe does it not eat at you? I’ve become so bitter at times it’s not funny and though I used be such a “fighter” I feel just tired of fighting. So how do you do it?

]]> Comment on Let’s Face the Music and Dance by Jackie Martinez http://www.mult-sclerosis.org/blog/?p=43#comment-286 Jackie Martinez Fri, 25 Nov 2011 17:20:14 +0000 http://www.mult-sclerosis.org/blog/?p=43#comment-286 WOW and how envy I your courage. I also have SPMS but am 32 and courage to do and try things I've seem to lost. I love dancing but as hard for me even stand days I don't get out much dance anymore, and worse my family/friends don't want go as much. I'm not sure if fear for me, embarrassment for me or for them? I'd be honored if tell me when you decided to just do it and give that first lesson a try? Any tips would be most helpful. Congrats and I hope you get to dance all the nights away! WOW and how envy I your courage. I also have SPMS but am 32 and courage to do and try things I’ve seem to lost. I love dancing but as hard for me even stand days I don’t get out much dance anymore, and worse my family/friends don’t want go as much. I’m not sure if fear for me, embarrassment for me or for them?

I’d be honored if tell me when you decided to just do it and give that first lesson a try? Any tips would be most helpful.

Congrats and I hope you get to dance all the nights away!

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